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Home > Pre-Reg Pharmacist > Drugs with Anticholinergic Properties

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Drugs with Anticholinergic Properties


Listed below are examples of drugs that have anticholinergic properties:

Anti-arrhythmic Drugs

  • Procainamide
  • Disopyramide

Antihistamines

  • Chlorphenamine
  • Diphenhydramine
  • Cyproheptadine
  • Hydroxyzine
  • Promethazine

Antidepressants

  • Amitriptyline
  • Dosulepin
  • Doxepin
  • Clomipramine
  • Imipramine
  • Nortriptyline

Antipsychotics

  • Chlorpromazine
  • Clozapine
  • Olanzapine

Bronchodilators

  • Ipratropium
  • Tiotropium

Drugs for urinary frequency, enuresis and incontinence

  • Flavoxate
  • Oxybutynin
  • Solifenacin
  • Tolterodine
  • Darifenacin
  • Trospium
  • Propiverine

Antiparkinson

  • Trihexyphenidyl (benzhexol)
  • Orphenadrine
  • Amantadine

Mydriatics and Cycloplegics

  • Atropine
  • Cyclopentolate
  • Tropicamide
  • Homatropine

Antiemetics

  • Hyoscine hydrobromide
  • Prochlorperazine

Antispasmodics

  • Dicycloverine
  • Hyoscine butylbromide
  • Propantheline

Skeletal Muscle Relaxants

  • Methocarbamol

Antidiarrhoeals

  • Diphenoxylate

Drugs that have anticholinergic properties may have the potential to cause anticholinergic side effects. Listed below are examples of some anticholinergic side effects:

  • Dry mouth
  • Difficulty in swallowing
  • Constipation
  • Paralytic ileus
  • Nausea or vomiting
  • Increased heart rate
  • Urinary retention
  • Difficulty in urinating
  • Blurred vision
  • Dry eyes
  • Exacerbation or precipitation of acute angle-closure glaucoma
  • Decreased sweating
  • Drowsiness or sedation
  • Dizziness
  • Hallucinations
  • Deliriums
  • Restlessness
  • Irritability
  • Nervousness
  • Slurred speech
  • Impaired concentration
  • Confusion
  • Memory impairment

 

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