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Home > Pre-Reg Pharmacist > Drug Induced Lung Disease

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Drug Induced Lung Disease


The table below lists some drugs known to cause drug induced lung disease

Drug Pulmonary Syndromes
Amiodarone Interstitial pneumonitis or pulmonary fibrosis, pleural effusions, pulmonary infiltrate with eosinophilia, bronchiolitis obliterans organising pneumonia, postoperative ARDS (acute respiratory distress syndrome)
Angiotensin-converting enzyme (ACE) inhibitors e.g. ramipril, enalapril, lisinopril, perindopril Dry cough
Beta-blockers e.g. propranolol, timolol Bronchospasm
Protamine Pulmonary oedema
Ergot-derived dopamine-receptor agonists e.g. bromocriptine, cabergoline Pulmonary fibrosis, pleural disease
Aspirin and other non-steroidal anti-inflammatory drugs (NSAIDs) e.g. ibuprofen Bronchospasm
Methotrexate Interstitial pneumonitis, pulmonary fibrosis, pulmonary oedema, pleuritic pain, pleural thickening
Nitrofurantoin Interstitial pneumonitis, pulmonary fibrosis, hypersensitivity lung reactions, pleural effusion, bronchospasm
Infliximab Respiratory tract infection, pulmonary oedema, bronchospasm, pleurisy, pleural effusion, pulmonary fibrosis
Mitomycin C Interstitial pneumonitis, pulmonary fibrosis, bronchospasm
Bleomycin Interstitial pneumonitis, pulmonary fibrosis

 

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