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Home > Pre-Reg Pharmacist > Therapeutic Drug Monitoring

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Therapeutic Drug Monitoring


Carbamazepine

Therapeutic range Approximate time to steady state Sampling time
4-12 mg/L 14-28 days after starting therapy
2-4 days after a dose change
Pre-dose

 

Digoxin

Therapeutic range Approximate time to steady state Sampling time
0.8 -2.0 mcg/L 7 Days At least 6 hours post dose

 

Lithium

Therapeutic range Approximate time to steady state Sampling time
0.4-1.0 mmol/L 4-7 days 12 hours after evening dose

 

Phenobarbital

Therapeutic range Approximate time to steady state Sampling time
15-40mg/L 14-28 days Pre-dose

 

Phenytoin

Therapeutic range Approximate time to steady state Sampling time
10 - 20mg/L 7-28 days (varies considerably between patients Pre-dose

 

Theophylline

Therapeutic range Approximate time to steady state Sampling time
10 - 20mg/L 2 days m/r preps, 4-6 hours post-dose

 

Aminophylline Infusion

Therapeutic range Approximate time to steady state Sampling time
10 - 20mg/L 1 day Sampling time not critical

 

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