Drugs to Avoid or Use With Caution in Glaucoma (including over-the-counter [OTC] medicines)

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Here is a list of drugs that should be avoided or used with caution in people with angle-closure glaucoma.

  • Antimuscarinics e.g.
    • Darifenacin
    • Fesoterodine
    • Flavoxate
    • Oxybutynin
    • Tolterodine
    • Ipratropium
    • Tiotropium
    • Glycopyrronium bromide
    • Umeclidinium
    • Aclidinium
    • Hyoscine
    • Dicycloverine
    • Atropine
    • Procyclidine
    • Orphenadrine
    • Propantheline
  • Antihistamines e.g.
    • Cyclizine
    • Chlorphenamine
    • Hydroxyzine
    • Pizotifen
    • Promethazine
  • Tricyclic antidepressants e.g.
    • Amitriptyline
    • Doxepin
    • Dosulepin
    • Clomipramine
  • Selective serotonin re-uptake inhibitors (SSRIs) e.g.
    • Citalopram
    • Sertraline
    • Fluoxetine
  • Antipsychotic drugs e.g.
    • Clozapine
    • Quetiapine
  • Tetracyclic antidepressants
    • Mirtazepine
    • Mianserin
  • Antiepileptics
    • Carbamazepine
    • Topiramate
  • Sympathomimetics e.g
    • Pseudoephedrine
    • Phenylephrine
    • Xylometazoline
  • Centrally acting sympathomimetics e.g.
    • Atomoxetine
    • Methylphenidate

In addition to the above, here are some OTC medicines listed below that should be avoided or used with caution in people with angle-closure glaucoma.

  • Antihistamines
    • Chlorphenamine (e.g. Piriton)
    • Diphenhydramine (e.g. Benylin Chesty Coughs [Original])
    • Promethazine hydrochloride (e.g. Sominex)
    • Promethazine teoclate (e.g. Avomine)
    • Triprolidine (e.g. Multi-Action Actifed Dry Coughs)
    • Buclizine (e.g. Migraleve Pink)
    • Antazoline (e.g. Otrivine Antistin Eye Drops)
  • Decongestants
    • Pseudoephedrine (e.g. Sudafed Decongestant)
    • Phenylephrine (e.g. Sudafed Sinus Max Strength)
  • Phenothiazines
    • Prochlorperazine (e.g. Buccastem M)
  • Anticholinergics
    • Hyoscine hydrobromide (e.g. Kwells)
    • Hyoscine butylbromide (e.g. Buscopan IBS Relief)
  • Corticosteroids
    • Beclometasone (e.g. Beconase Hayfever Nasal Spray)
    • Fluticasone (e.g. Pirinase Hayfever Nasal Spray)
    • Triamcinolone (e.g. Nasacort Allergy Nasal Spray)

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